![Design, synthesis, and biological evaluation of polo-like kinase 1/eukaryotic elongation factor 2 kinase (PLK1/EEF2K) dual inhibitors for regulating breast cancer cells apoptosis and autophagy - Eur. J. Med. Chem. - X-MOL Design, synthesis, and biological evaluation of polo-like kinase 1/eukaryotic elongation factor 2 kinase (PLK1/EEF2K) dual inhibitors for regulating breast cancer cells apoptosis and autophagy - Eur. J. Med. Chem. - X-MOL](https://xpic.x-mol.com/20171215%2F10.1016_j.ejmech.2017.12.046.jpg)
Design, synthesis, and biological evaluation of polo-like kinase 1/eukaryotic elongation factor 2 kinase (PLK1/EEF2K) dual inhibitors for regulating breast cancer cells apoptosis and autophagy - Eur. J. Med. Chem. - X-MOL
![Figure 2 from Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. | Semantic Scholar Figure 2 from Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. | Semantic Scholar](https://ai2-s2-public.s3.amazonaws.com/figures/2017-08-08/22a093811fa1404a83b7a26e3330d029c694d545/3-Figure2-1.png)
Figure 2 from Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. | Semantic Scholar
![Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis | PNAS Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis | PNAS](https://www.pnas.org/content/108/22/9310/F1.large.jpg)
Continuous polo-like kinase 1 activity regulates diffusion to maintain centrosome self-organization during mitosis | PNAS
![Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization | PNAS Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization | PNAS](https://www.pnas.org/content/pnas/104/9/3107/F5.large.jpg)
Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization | PNAS
![Figure 3 from Polo-like kinases: structural variations lead to multiple functions | Semantic Scholar Figure 3 from Polo-like kinases: structural variations lead to multiple functions | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/c69c63e232fe5d05c665808f0c485d5f3ff15102/8-Figure3-1.png)
Figure 3 from Polo-like kinases: structural variations lead to multiple functions | Semantic Scholar
![Frontiers | A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas | Oncology Frontiers | A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas | Oncology](https://www.frontiersin.org/files/MyHome%20Article%20Library/492867/492867_Thumb_400.jpg)
Frontiers | A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas | Oncology
![Genes | Free Full-Text | The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor? | HTML Genes | Free Full-Text | The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor? | HTML](https://www.mdpi.com/genes/genes-10-00208/article_deploy/html/images/genes-10-00208-g001.png)
Genes | Free Full-Text | The Mitotic Cancer Target Polo-Like Kinase 1: Oncogene or Tumor Suppressor? | HTML
![Figure 1 from Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. | Semantic Scholar Figure 1 from Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/22a093811fa1404a83b7a26e3330d029c694d545/2-Figure1-1.png)
Figure 1 from Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology. | Semantic Scholar
![Polo-like kinases: conservation and divergence in their functions and regulation | Nature Reviews Molecular Cell Biology Polo-like kinases: conservation and divergence in their functions and regulation | Nature Reviews Molecular Cell Biology](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fnrm2653/MediaObjects/41580_2009_Article_BFnrm2653_Fig1_HTML.jpg)
Polo-like kinases: conservation and divergence in their functions and regulation | Nature Reviews Molecular Cell Biology
![Cancers | Free Full-Text | The Emerging Role of Polo-Like Kinase 1 in Epithelial-Mesenchymal Transition and Tumor Metastasis | HTML Cancers | Free Full-Text | The Emerging Role of Polo-Like Kinase 1 in Epithelial-Mesenchymal Transition and Tumor Metastasis | HTML](https://www.mdpi.com/cancers/cancers-09-00131/article_deploy/html/images/cancers-09-00131-g001.png)
Cancers | Free Full-Text | The Emerging Role of Polo-Like Kinase 1 in Epithelial-Mesenchymal Transition and Tumor Metastasis | HTML
![Structure and function of the human Polo-like kinases: (A) Polo-like... | Download Scientific Diagram Structure and function of the human Polo-like kinases: (A) Polo-like... | Download Scientific Diagram](https://www.researchgate.net/publication/334148435/figure/fig1/AS:775911792197632@1562003195090/Structure-and-function-of-the-human-Polo-like-kinases-A-Polo-like-kinases-in-human.png)
Structure and function of the human Polo-like kinases: (A) Polo-like... | Download Scientific Diagram
![Role of polo-like kinase 1 (PLK1) overexpression in cancer. In addition... | Download Scientific Diagram Role of polo-like kinase 1 (PLK1) overexpression in cancer. In addition... | Download Scientific Diagram](https://www.researchgate.net/publication/320073741/figure/fig1/AS:543603208069120@1506616512716/Role-of-polo-like-kinase-1-PLK1-overexpression-in-cancer-In-addition-to-its-role-in.png)
Role of polo-like kinase 1 (PLK1) overexpression in cancer. In addition... | Download Scientific Diagram
![Polo-like kinases: structural variations lead to multiple functions | Nature Reviews Molecular Cell Biology Polo-like kinases: structural variations lead to multiple functions | Nature Reviews Molecular Cell Biology](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fnrm3819/MediaObjects/41580_2014_Article_BFnrm3819_Fig1_HTML.jpg)